How is clinical presentation of RCC?

Incidental 50% Local Tumor Growth (Hematuria, Flank pain, Abdominal mass, Perirenal hematoma) Metastases (Persistent cough, Bone pain, Cervical lymphadenopathy, Constitutional symptoms, Weight loss/fever/malaise) Obstruction of the Inferior Vena Cava (Bilateral lower extremity edema, Nonreducing or right-sided varicocele) Paraneoplastic Syndromes (Hypercalcemia, Hypertension, Polycythemia, Stauffer’s syndrome( abnormal liver function tests))