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Pharmacology

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Pregunta:

How is uptake and distribution of inhaled anesthetics?

Autor: H K



Respuesta:

Alveolar Wash in (replace normal gases w/anesthetic as partial pressure increases transfer begins) Anesthetic Uptake (related to solubility in blood [ if low like N2O then few molecules are needed to increase PP, achieve steady state rapidly, if high (halothane) less time needed], Cardiac output [lower == slower delivery], Alveolar-venous PP gradient [if higher gradient between blood and alveoli higher uptake]) Effect of different tissue types (organ w/high perfusion faster flow [brain, heart, liver, spleen...], poor perfusion slow flow [muscles]) Washout (NO2 exits faster than halothane)


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Autor

H K
H K