Pregunta:
How are pharmacokinetics of statins?
Autor: H KRespuesta:
Oral absorption is variable and High plasma protein binding Metabolism: Atorvastatin, Lovastatin and simvastatin are primarily metabolized by CYP3A4 Pravastatin and Rosuvastatin: insignificantly metabolized by CYP Plasma half life: Atorvastatin (14 h) and Rosuvastatin (19h) have long t1/2, the others 1-2 h
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