Pregunta:
What is mechanism of action of class IA agents?
Autor: H KRespuesta:
Quinidine binds to open and inactivate Na+ channels prevent Na+ influx in phase 0, slows the rate of depolarization and conduction, prolong repolarization by blocking some K+ channels, increase ventricular effective refractory period ERP, slows conduction Other actions (mild a antagonist and anticholinergic)
0 / 5 (0 calificaciones)
1 answer(s) in total