Pregunta:
How is mechanism of action of ARBs (angiotensin receptor blockers?
Autor: H KRespuesta:
These drugs have very similar effects to ACE inhibitors and are used for the same indications ARBs are receptor antagonists that block type 1 angiotensin II (AT1) receptors on bloods vessels and other tissues such as the heart. AT1 receptors are coupled to the Gq-protein and IP3 signaltransduction pathway that stimulates vascular smooth muscle contraction.
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