How are epinephrine interactions?

A. Cocaine: In the presence of cocaine, epinephrine produces exaggerated cardiovascular actions. b. Diabetes: Epinephrine increases the release of endogenous stores of glucose. In the diabetic, dosages of insulin may have to be increased. c. β-Blockers: prevent epinephrine’s effects on β receptors, leaving α-receptor stimulation unopposed. It leads to an increase in peripheral resistance and an increase in blood pressure