What are gross anatomical abnormalities of schizophrenia?

Increased size of ventricles ((lateral and 3rd) and decreased brain volume is the most replicated finding, Ventricular enlargement is found in affected twins of monozygotic pairs discordant for schizophrenia, This enlargement appears to be stable when patients are followed up prospectively) Decreased cortical gray matter (Especially evident in superior temporal gyrus, dorsal prefrontal cortex and limbic areas such as the hippocampal formation and anterior cingulate cortex. These abnormalities may be present in first-episode, never-medicated patients)