What are neurodevelopmental abnormalities in schizophrenia?

Subtle molecular abnormalities and schizophrenia. The "subtlety" of molecular abnormalities may vary, with some leading to psychiatric symptoms in the presence of minimal environmental stress and others requiring multiple major stressors to cause mental illness. For example, the aggregate of symptoms that make up the schizophrenia syndrome may be more biologically determined than that of other psychiatric illnesses. In this case, perhaps only minor stressors acting on very high risk circuits would be enough to activate symptoms of schizophrenia.