How is thrombin generation and regulation of coagulation?

Thrombin Generation: Thrombin plays a central role in the coagulation cascade by converting soluble fibrinogen into insoluble fibrin strands, which cross-link to form a stable fibrin clot. Regulation of Coagulation: Coagulation is tightly regulated by anticoagulant factors such as antithrombin, protein C, and protein S, which inhibit the activity of thrombin and factors Va and VIIIa, thus preventing excessive clot formation