What is chronic lymphoid leukemia?

Neoplasm of maturing peripheral lymphocytes, may present as concurrent or isolated lymphoma (SLL), bone marrow always involved, spleen and liver can also be involved Pathogenesis (disrupts normal immune function lead to hypogammaglobulinemia and increased infections, autoimmune hemolytic anemia (AIHA) and immune thrombocytopenic purpura (ITP). Some transform to more aggressive forms like prolymphocytic transformation and Richter syndrome [transformation to diffuse large B cell lymphoma]