Pregunta:
What is chronic myelogenous leukemia (CML)?
Autor: H KRespuesta:
Presence of philadelphia chromosome t(9,22), results of fusion of BCR and ABL genes, ABL gene is tyrosine kinase that controls cell growth, BCR/ABL fusion protein results in increased, unregulated activity of ABL leading to uncontrolled growth of maturing myeloid cells
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Autor
H K