Pregunta:
How is pathogenesis of acute leukemia?
Autor: H KRespuesta:
Recurrent cytogenetic abnormalities (t(15;17) - acute promyelocytic leukemia [M3] t(8;21) - acute myelobastic leukemia w/maturation [M2], 11q23 abnormalities Genetic abnormalities lead to defects in stem cell maturation and clonal expansion of leukemic blasts
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