What are causes of hemolysis?

Intrinsic or extrinsic to RBCs (intracorpuscular vs. extracorpuscular defects), inhertited or acquired, acute or chronic, immune destruction (AB) or non-immune mechanism, intravascular vs extravascular (in vasculature or in reticuloendothelial macrophages in liver and spleen), most of inherited conditions are intracapsular and most of hemolysis by an immune mechanism is extravascular. Reticulocytosis requires adequate iron and vitamins (B12, folate) for RBC production. Normally functional bone marrow and adequate EPO production