What is acute adrenocortical insufficiency?

Massive adrenal hemorrhage may destroy enough of the adrenal cortex to cause acute adrenocortical insufficiency. This condition may occur in patients maintained on anticoagulanttherapy, in postoperative patients who develop disseminated intravascular coagulation, during pregnancy, and in patients suffering from overwhelming sepsis; Waterhouse- Friderichsen  Syndrome Neisseria meningitidis +++; but also pseudomonas, pneumococci, haemophilus influenzae. Rapidly progressive Hypotension IVDC with purpura Massive adrenal hemorrhage . Any age preferentially in children