What is adrenal cortical congenital hyperplasia?

Congenital metabolic dysfonction Autosomal recessive F = H Responsible for the majority of androgenital syndromes in the first year of life Clinically: in 95% pure virilizing syndrome with in 30% of electrolyte disturbances The changes in CS are identical regardless of the enzymatic defect: diffuse hyperplasia of the RZ