What are vascular mechanisms of HTN?

• In hypertensive patients， structural， mechanical， or functional changes may reduce the lumen diameter of small arteries and arterioles • Hypertrophic or eutrophic vascular remodeling results in decreased lumen size and， hence， increased peripheral resistance. • Vessels with a high degree of elasticity can accommodate an increase of volume with relatively little change in pressure， whereas in a semirigid vascular system， a small increment in volume induces a relatively large increment of pressure