What are actions and therapeutic uses of Succinylcholine?

Short-lasting muscle fasiculation and few minutes of paralysis, no ganglionic block unless high doses, weak histamine-release action, duration of action is short, due to rapid breaking by plasma cholinesterase. If they get into neuroskeletal junction they cannot be degraded so they bind to nicotinic receptors and redistribution to plasma is necessary for metabolism Note that genetics may increase or decrease plasma cholinesterase levels It is useful in rapid endotracheal intubation required during anethesia.