How is venous thrombosis?

Main trigger (Stasis), slowing venous flow seen in disorders of prolonged recumbency, increased by disorders of tone of venous wall (varicose) slowing of CO (HF) or venous compression. Can be associated w/damage to endothelium by toxins (inflammatory and infectious foci thrombus). Main consequence is local stasis (edema and tissue trophic disorders) and risk of PE for deep vein thrombosis. occlusive, travel a distant to heart forming long trial in lumen of vessel likely to give embolisms. more embedded in RBC since slow venous circulation (red thrombi), mostly veins of lower limb (90%) but can occur in upper extremities/periprostatic plexus/ovarian/periuterine veins. Special circumstance (dural sinuses, portal vein, or hepatic vein)