What are shock lesions in different organs?

➢ Kidney: massive cortical ischemia or disseminated epithelial necrosis (NTA) ➢ Myocardium: ischemia followed by localized or generalized necrosis. ➢ Lungs: especially severe in septic shock: DAD (diffuse alveolar damage) ➢ Liver: ischemic necrosis in the hepatocyte layer, in the centro-lobular regions, steatosis (sign of hypoxia). ➢ Gastrointestinal tract: mucous erosions or large hemorrhagic gastric and duodenal ulcerations ➢ Adrenals: Delipidation of superficial areas; Acute hemorrhage ➢ Brain: Ischemic encephalopathy, generalized or multifocal, followed by cerebral softening. Laminar necrosis of the hemispheric cortex ➢ Capillaries: disseminated intravascular coagulation ➢ During irreversible shock, necrosis lesions of the regions sensitive to anoxia are visible within a few days (kidney, myocardium, brain)