TOXICOLOGY: (TYPE OF REACTIONS)

1 irreversible. It permanently alters endogenous
molecules.

2 COMMON WITH ELECTROPHILIC TOXICANTS such as nonionic and cationic electrophiles and radical cations.
.
3 These TOXICANTS REACT WITH NUCLEOPHILIC ATOMS that are abundant in biological macromolecules, such as proteins and nucleic acids. Neutral free radicals such as HO• , •NO2 , and
Cl3C• also can bind covalently to
biomolecules.

Question

(TYPE OF REACTIONS)

1 irreversible. It permanently alters endogenous
molecules.

2 COMMON WITH ELECTROPHILIC TOXICANTS such as nonionic and cationic electrophiles and radical cations.
.
3 These TOXICANTS REACT WITH NUCLEOPHILIC ATOMS that are abundant in biological macromolecules, such as proteins and nucleic acids. Neutral free radicals such as HO• , •NO2 , and
Cl3C• also can bind covalently to
biomolecules.

LEIGHTON DWIGHT OBILLOS · Accepted Answer

. (Covalent binding)

1 Covalent binding

2 Covalent adduct formation

3 ELECTROPHILIC TOXICANTS

TOXICOLOGY

. (Covalent binding) 1 Covalent binding 2 Covalent adduct formation 3 ELECTROPHILIC TOXICANTS

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