TOXICOLOGY: A. ABSORPTION VS PRESYSTEMIC
ELIMINATION

1 is the process by which a CHEMICAL IS TRANSFERRED FROM THE SITE OF EXPOSURE, usually an internal or external body surface, INTO the SYSTEMIC CIRCULATION.

2 Factors that influence this:

Question

A. ABSORPTION VS PRESYSTEMIC
ELIMINATION

1 is the process by which a CHEMICAL IS TRANSFERRED FROM THE SITE OF EXPOSURE, usually an internal or external body surface, INTO the SYSTEMIC CIRCULATION.

2 Factors that influence this:

LEIGHTON DWIGHT OBILLOS · Accepted Answer

1 Absorption

2  Concentration 
 Surface area of exposure 
 Characteristics of the epithelial layer through which
the toxicant is being absorbed 
 lipid solubility (MOST IMPORTANT)

TOXICOLOGY

A. ABSORPTION VS PRESYSTEMIC ELIMINATION 1 is the process by which a CHEMICAL IS TRANSFERRED FROM THE SITE OF EXPOSURE, usually an internal or external body surface, INTO the SYSTEMIC CIRCULATION. 2 Factors that influence this:

1 Absorption 2  Concentration  Surface area of exposure  Characteristics of the epithelial layer through which the toxicant is being absorbed  lipid solubility (MOST IMPORTANT)

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