What are pathways of metastasis of neoplasms?

Seeding w/in body cavity (invade body cavity, cancers of ovary invade peritoneum, or CNS neoplasm (medulloblastoma/ ependynoma) go to cerebral ventricles by CSF to meninges/ spinal cord) Lymphatic spread (more typical, favored by sarcoma, pattern depends on site of tumor, lung carcinoma spread to regional bronchial nodes then hilar, breast go to axillary nodes, medial breast to nodes along internal mammary artery, and thus supra and infraclavicular nodes are seeded, some cases witness skip metastasis Sentinel lymph node (first one to recieve tumor) can be identified by dyes near primary tumor, biopsy of it gives spread info use to plan tx, enlargement doesn't always mean metastasis) Hematogenous spread (carcinoma, liver and lungs most frequent sites of metastasis here, near vertebra embolize through paravertebral plexus go to thyroid and prostate