What is sideroblastic anemia (SA)?

Group of inherited and acquired anemia, iron accumulates in mitochondria of erythrocyte precursors. Inherited (X recessive, more in males, abnormality synthesis of protoporphyrin decreased Hb, iron accumulated cause ring sideroblast, iron laden mitochondria ring around nucleus of RBC precursor in bone marrow, basophilic stippling in peripheral smear (no2at)), Acquired (alcoholism, B6 deficiency, lead poisoning, Cu deficiency, age>74)