How is LDL pathophysiology intracellular?

LDL containing cholesterol esters and ApoB100 are endocytosed to peripheral tissues and liver, get into lysosome, and give cholesterol to cell, which have many pathways, ACAT lead to cholesterol storage, HMG-CoA reductase induces synthesis of cholesterol is inhibited by increased cholesterol stored, and same mechanism for LDL receptors (decrease w/increase in cholesterol intracellular