Pregunta:
How is theophylline used in asthma management?
Autor: H KRespuesta:
Adjunct for pt with failed corticosteroid treatment, weak bronchodilation and anti-inflammatory effect, inhibit phosphodiesterase increasing cAMP. We should monitor blood levels to avoid toxicity (especially elderly - GI side effects 20-30 microg/ml, cardiac arrhythmias, seizures, blood glucose 8-15 therapeutic)
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