Pregunta:
What are the causes of central DI?
Autor: H KRespuesta:
Genetic abnormality of vasopressin gene (familial DI) (occurs in childhood, polyuria, due to abnormal folding of vasopressin it accumulates in ER of neurons, genetic testing done to diagnose.) Mass lesion of neurohypophysis (craniopharyngioma, metastasis, lymphoma) Granulomatous disease Idiopathic Autoimmune Surgery or Trauma of neurohypophyseal system.
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