MANUFACTURE FINALS:  The PRIMARY POWDER PARTICLES are AGGREGATED under a HIGH PRESSURE

 Usually DONE THROUGH SLUGGING (a heavy-duty tablet press is used and the resulting product is a large tablet that is broken down into smaller pieces) or ROLLER COMPACTION (the powder is squeezed between 2 rollers to produce sheet of materials that will be broken down into smaller pieces)
 This method may be USED FOR DRUGS THAT DO NOT COMPRESS WELL AFTER WET GRANULATION or those which are SENSITIVE TO MOISTURE
 Active tablets are usually Thiamine, Thiamine hydrochloric, Aspirin, Ascorbic acid, and Magnesium
hydroxide

(STATE THE ADV & DISADV)

Question

 The PRIMARY POWDER PARTICLES are AGGREGATED under a HIGH PRESSURE

 Usually DONE THROUGH SLUGGING (a heavy-duty tablet press is used and the resulting product is a large tablet that is broken down into smaller pieces) or ROLLER COMPACTION (the powder is squeezed between 2 rollers to produce sheet of materials that will be broken down into smaller pieces)
 This method may be USED FOR DRUGS THAT DO NOT COMPRESS WELL AFTER WET GRANULATION or those which are SENSITIVE TO MOISTURE
 Active tablets are usually Thiamine, Thiamine hydrochloric, Aspirin, Ascorbic acid, and Magnesium 
hydroxide

(STATE THE ADV & DISADV)

LEIGHTON DWIGHT OBILLOS · Accepted Answer

Dry Granulation

adv: 
Very useful for water and heat-sensitive materials

disadv: 
1  NOT permit uniform color distribution
2 tendency to CREATE MORE DUST (NO GRANULATING FLUID)

MANUFACTURE FINALS

Dry Granulation adv: Very useful for water and heat-sensitive materials disadv: 1 NOT permit uniform color distribution 2 tendency to CREATE MORE DUST (NO GRANULATING FLUID)

Autor