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Endocrinology

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Pregunta:

How is the pathophysiology of Hirsuism?

Autor: H K



Respuesta:

We have overproduction of testosterone and delta-4- androstendione For testosterone: it can be from ovarian or extra-ovarian origin as the production of 1/3 of testosterone is from ovary and 2/3 is at extraovarian (by bioconversion of delta 4 androstendione in skin, adrenals and lipid...) they diffuse to cells and become DHT by 5a reductase Delta-4- androstendione produced by ovaries and adrenals in equal proportions (50/50)


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Autor

H K
H K