Are the two traditional anticoagulants used for acute coronary syndromes, deep-vein thrombosis (DVT), pulmonary embolism (PE), and heart surgery Also given to certain people at risk for forming blood clots, such as those with artificial heart valves or who have atrial fibrillation (AF)intravascular coagulation of the blood in any part of the circulatory system, as in the heart, arteries, veins, or capillaries