PHARMACOLOGY 1: • PGE1

• CA: for CHRONIC IDIOPATHIC CONSTIPATION, opioid-induced constipation; and irritable bowel syndrome with constipation

• MOA: stimulates chloride channel in the luminal cells of the
intestinal epithelium, thereby increasing intestinal fluid
secretion

Question

• PGE1

• CA: for CHRONIC IDIOPATHIC CONSTIPATION, opioid-induced  constipation; and irritable bowel syndrome with constipation

• MOA: stimulates chloride channel in the luminal cells of the 
intestinal epithelium, thereby increasing intestinal fluid 
secretion

LEIGHTON DWIGHT OBILLOS · Accepted Answer

LUBIPROSTONE

• PGE1 • CA: for CHRONIC IDIOPATHIC CONSTIPATION, opioid-induced constipation; and irritable bowel syndrome with constipation • MOA: stimulates chloride channel in the luminal cells of the intestinal epithelium, thereby increasing intestinal fluid secretion