PHARMACOLOGY 1: • MOA: Binds briefly to active site of AChE and prevents access of ACh

• Effects: Amplifies all actions of ACh (increases parasympathetic activity and somatic neuromuscular
transmission)

• CA: Diagnosis and acute treatment of myasthenia gravis

• Toxicity: Parasympathomimetic excess

Question

• MOA: Binds briefly to active site of AChE and prevents access of ACh

• Effects: Amplifies all actions of ACh (increases parasympathetic activity and somatic neuromuscular 
transmission)

• CA: Diagnosis and acute treatment of myasthenia gravis

• Toxicity: Parasympathomimetic excess

LEIGHTON DWIGHT OBILLOS · Accepted Answer

EDROPHONIUM

• Tensilon®

• MOA: Binds briefly to active site of AChE and prevents access of ACh • Effects: Amplifies all actions of ACh (increases parasympathetic activity and somatic neuromuscular transmission) • CA: Diagnosis and acute treatment of myasthenia gravis • Toxicity: Parasympathomimetic excess