Controlling Gene Expression: As epigenetic changes can activate or silence specific genes, it follows that the protein enzymes that are key in methylation and acetylation provide a potential target for drug development.
How could increased methylation result in tumour development

Question

As epigenetic changes can activate or silence specific genes, it follows that the protein enzymes that are key in methylation and acetylation provide a potential target for drug development.
How could increased methylation result in tumour development

Paul Bishop · Accepted Answer

Increased methylation could result in reduced activity of tumour suppressor gene, leading to increased, uncontrolled cell division.

Controlling Gene Expression

As epigenetic changes can activate or silence specific genes, it follows that the protein enzymes that are key in methylation and acetylation provide a potential target for drug development. How could increased methylation result in tumour development

Increased methylation could result in reduced activity of tumour suppressor gene, leading to increased, uncontrolled cell division.

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