Post-Translation polypeptide modification

- Polypeptide chains are modified after translation or targeted to specific sites in the cell​ - During synthesis, a polypeptide chain begins to coil and fold spontaneously into a specific shape: a three-dimensional molecule with secondary and tertiary structure - During synthesis, a polypeptide chain begins to coil and fold spontaneously into a specific shape: a three-dimensional molecule with secondary and tertiary structure​​ - Post-translational modifications may be required before the protein can begin doing its particular job in the cell​