Transmission of Buruli ulcer

In endemic regions, the disease is highly focal and usually associated with wetlands or coastal regions. PCR testing of environmental samples, such as water, aquatic plants, soil, and detritus from swamps, has found evidence of M. ulcerans. Insects such as mosquitoes7 and waterresiding biting arthropodshave been associated with M. ulcerans. A. Difficult to isolate Mu from nvironmental samples, B. Lesions in children less indicative of specific exposure patterns C. Conflicting evidence for vector transmission i.e. lab based infection studies but experiments suggested skin trauma.