Non pharmacolgogic: Exercise, CBT, Yoga, acupuncture, TCA ( Amitriptyline 25 mg QHS along with Fluoxetine 20 mg in am Gabapentin 2/3 dose in pm and 1/3 in am Pregabalin ( Lyrica) is newest approved by $$$ Tramadol may help. Cyclobenzaprine 5 mg given 3 hours before bed to minimize grogginess. Cannabinoids oral better than inhaled. SNRI: Duloxetine or Effexor