After acute attack subsided. If at least 2 flares/ year, tops or nephrolitiasis. Start allopurinol for uric acid elevation, but wait until acute attack subsided. Continue NSAID for 3 mo to prevent attack. Can determine if overproducing UA by checking a 24 urine uric acid level. > 750 indicates overproduction and allopurinol would be indicated. Do not treat asymptomatic elevated UA.