Lipase x3 nl ( specific), amylase ( nonspecific), CRP (predicts severity), US to check for gallstones, CT with contrast is gold standard, ERCP if have elevated bili > 5 Other labs in w/u: LFT, CBC, TG, UA and ABG, CXR to r/o PUD, Cholecystitis, Perforation, hepatitis, mesenteric ischemia