How are the clinical manifestations different from most diseases caused by antibodies specific for cell surface or tissue matrix proteins?

Type III hypersensitivity:Diseases Caused By Antigen-Antibody Complexes: -systemic lupus erythematosus, polyarteritis nodosa, serum sickness. Complexes containing positively charged antigens are particularly pathogenic because they bind avidly to negatively charged components of the basement membranes of blood vessels and kidney glomeruli.