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L-12 Modeling protein Structure

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Pregunta:

What are the limitations of predicting proteins structure?

Autor: Shay 1vcc



Respuesta:

• Not all proteins or parts of proteins assume a well- defined 3D structure in solution. • Protein structure is not static, there are various degrees of thermal motion for different parts of the structure. • There may be a number of slightly different conformations in solution. • Some proteins undergo conformational changes when interacting with STUFF.


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