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level: TOXICOLOGY 1 - HEAVY METALS

Questions and Answers List

Question	Answer
One of the oldest occupational & environmental diseases in the world	Lead
Type of Lead which is poorly absorbed in the skin	Inorganic Lead
TRUE / FALSE. Inorganic lead is slowly & consistently being absorbed by the 1. RESPIRATORY tract & 2. GASTROINTESTINAL tract	TRUE
TRUE / FALSE. Adults are more susceptible to Inorganic Lead poisoning	FALSE - children are more prone
99% of Lead gets bound to what type of cells?	Erythrocytes / RBCs
70% of Lead clearance / excretion occurs in the ________	Kidney - 70% gets excreted in the urine
Long term exposure of Lead could lead to ________	Neurocognitive effects
> 30 mcg/dl of Lead (Acute)	neurocognitive effects, sleep disturbance
> 100 mcg/dl of Lead (Acute)	Lead Encephalopathy
Chronic high dose exposure to Lead	Peripheral neuropathy
What is the effect of Lead upon the systolic & diastolic blood pressure?	Hypertension / increases in BP
Effects of Lead on the GIT?	1. Lead colick, 2. Gingival Lead Lines
This type of lead poisoning targets the CNS & produces dose-dependent effects	Organolead poisoning