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Index
»
PHARMA_2F - TOXICOLOGY 1
»
Chapter 1
»
TOXICOLOGY 1 - HERBICIDES
level: TOXICOLOGY 1 - HERBICIDES
Questions and Answers List
level questions: TOXICOLOGY 1 - HERBICIDES
Question
Answer
2,4-Dicholorophenoxiacetic acid / (2,4-D)
Chlorophenoxy
2,4,5-Tricholorophenoxyacetic acid / (2,4,5-T)
Chlorophenoxy
A herbicide (at large doses) which can cause coma, generalized weakness. It is associated with NON-HODGKIN'S LYMPHOMA
(2,4-D)
Most widely used herbicide; "contact herbicide"
Glyphosate
A TERATOGENIC contact herbicide which causes ESOPHAGEAL EROSION
Glyphosate
Single electron reduction of the herbicide to free radical species
Bipyridyl
Paraquat
Bipyridyl
A bipyridyl agent which (via INHALATION) accumulates slowly in the lungs, and then causes: PULMONARY EDEMA, PROGRESSIVE FIBROSIS & ALVEOLITIS
Paraquat
A bipyridyl agent which inhibits SUPEROXIDE DIMUTASE = intracellular free radical oxygen toxicity
Paraquat
Possible s/sx of Paraquat if INGESTED / ORAL EXPOSURE
bloody stools, hematemesis
"Delayed toxicity" of Paraquat
congestive hemorrhagic pulmonary edema