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level: Level 1 of HTA Methods

Questions and Answers List

level questions: Level 1 of HTA Methods

Question	Answer
2 main types of HTA Methods	1 Primary data method 2 Secondary data method or integrative methods OR synthesize methods
1 involves the collection of original data such as in methods of clinical trials or observational studies 2 involves combining data or information from existing sources including from the primary data	1 Primary Data methods 2 Secondary methods or integrative method or synthesize methods
it involves one or both of the primary data methods and secondary methods, this is the combination.	Economic analysis methods
Primary Data Studies: Diverse Attributes	1 Comparative vs. non-comparative 2 Separate control group (external factor) vs. no separate control group (internal) 3 Participants defined by a health outcome vs. by having been exposed to, or received or been assigned, an intervention 4 Prospective vs retrospective 5 Interventional vs. observational 6 Experimental vs. non-experimental 7 Random assignment vs. non-random assignment of px to treatment and control groups
1 (mostly this is an external factor) 2 (internal)	1 Separate control group 2 no separate control group
1 (aka study population)	1 Participants defined by a health outcome
1 (it watches for outcomes; this study usually involves taking a cohort of subjects and watching them for a long period) 2 (looks backwards and examines exposure to suspected risk or protection factors in relation to an outcome that is established at the start of the study)	1 Prospective 2 retrospective
1 (this involves a participant and you have given them 2 separate intervention) 2 (purely observation or everyone received treatment and you just have to observe each one of them)	1 Interventional 2 observational
a group is chosen sometimes as a random sample from a certain larger population and then the exposures of people in the group to an intervention and outcomes of interest are determined. So, this study, is design or used to assess the accuracy of diagnostic test	interventional cross-sectional observational study
studies which may be better for reflecting the real-world practice; have main attributes including comparison of clinically relevant alternative interventions or a diverse population of study participants and then participants recruited from the heterogenous practice settings and lastly, data collection from a broad range of health outcomes	Pragmatic clinical trials
a retrospective observational study designed to determine the related relationship between a particular outcome of interest and also a potential cause. In here the investigator identify a group of patients with a specified outcomes and a group of patients without a specified outcome.	Case control study