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level: Level 4 - ANTIFUNGALS

Questions and Answers List

level questions: Level 4 - ANTIFUNGALS

Question	Answer
MOA: Binds to ERGOSTEROL IN FUNGAL MEMBRANE causing membrane to become leaky	1 AMPHOTERICIN B Class of Antifungal: Polyene 2 NYSTATIN Class of Antifungal: Polyene
MOA: Inhibit CYP P450 14 α- demethylase in fungi. Ergosterol Biosynthesis Inhibitors	Azoles and Triazole Antifungal Agents
This enzyme is involved in the CONVERSION OF LANOSTEROL to ERGOSTEROL.	14α-demethylase
Five azole antifungals: are used in topical application only.	1 Miconazole, 2 Econazole, 3 Oxiconazole, 4 Sulconazole and 5 Tioconazole MEO ST
is SUPPLIED AS A CREAM or in SHAMPOOS at one- or two-percent, for the TREATMENT OF TINEA PEDIS, TINEA CORPORIS, TINEA CRURIS & CUTANEOUS CANDIDIASIS. (1-2%) (STATE THE Products OF THIS)	KETOCONAZOLE PRODUCTS: 1 Nizoral Cream, 2 Nizoral A-D Shampoo (1%), 3 Nizoral Shampoo (2%)
is TAKEN ORALLY IN CAPSULE FORM to TREAT FUNGAL INFECTIONS that START IN THE LUNGS and spread throughout the body. can also be used to TREAT FUNGAL INFECTIONS OF THE NAILS (STATE THE Products OF THIS)	ITRACONAZOLE Product: Sporanox
is a ONE-A-DAY TABLET or SUSPENSION TO TREAT YEAST INFECTIONS of the VAGINA, MOUTH, THROAT, ESOPHAGUS, ABDOMEN, LUNGS, BLOOD & OTHER ORGANS (STATE THE Products OF THIS)	FLUCONAZOLE Product: Diflucan
is a CREAM SUPPOSITORY used to TREAT VULVOVAGINITIS used either ONCE or in a SEVEN-DAY REGIMEN at bedtime. (STATE THE Products OF THIS)	BUTOCONAZOLE Product: Gynazole-1
Ergosterol Biosynthesis Inhibitors Antifungal Agents Targeting Squalene Epoxidase:	1 TERBINAFINE 2 TOLNAFTATE
comes as a TABLET TO TAKE ORALLY or as a TOPICAL CREAM, used to TREAT FUNGAL INFECTIONS OF THE NAILS. (STATE THE Products OF THIS)	TERBINAFINE Product: Lamisil
is a TOPICAL CREAM to TREAT TINEA INFECTIONS OF THE SKIN. (STATE THE Products OF THIS)	TOLNAFTATE Products: 1 Aftate, 2 Tinactin, 3 Ting, 4 Breezee
Inhibitors of Cell Division MOA: INHIBITS MICROTUBULE POLYMERIZATION thus INHIBITING the formation of the MITOTIC SPINDLE. is an antifungal produced from PENICILLIUM GRISEOFULVUM (STATE THE Products OF THIS)	GRISEOFULVIN Products: 1 Fulvicin-U/F, 2 Grifulvin V, 3 Gris-PEG