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level: Level 5 - TABLETS .2

Questions and Answers List

level questions: Level 5 - TABLETS .2

Question	Answer
- They are COMPRESSED GRANULAR EFFERVESCENT SALTS that are FORMED INTO A TABLET. - When they are mixed with water, there is liberation of carbon dioxide. Liberation acts as disintegrator. (GIVE EXAMPLE OF THIS)	Effervescent Tablet ex. - Ex: Fluimucil 600mg or Berocca. (They contain sodium bicarbonate or citric acid or tartaric acid)
Effervescent Tablet 1 (They contain sodium bicarbonate or citric acid or tartaric acid) 2 __ acts as disintegrator.	. 1 Fluimucil 600mg or Berocca. 2 Liberation
- These tablets are usually DISSOLVED AT THE CHEEKS OF YOUR MOUTH. - Formulated and compressed with SUFFICIENT PRESSURE to give a hard tablet. - SOME are formulated, TO MELT AT YOUR BODY TEMPERATURE WHICH GIVES A MORE RAPID ABSORPTION. - This approach is USED FOR POORLY SOLUBLE COMPOUNDS.	Buccal Tablet
- DISSOLVE UNDER THE TONGUE. - Formulated and compressed with sufficient pressure to give a hard tablet. - Some are formulated, to melt at your body temperature which gives a more rapid absorption. - This approach is USED FOR POORLY SOLUBLE COMPOUNDS.	Sublingual
- These are drugs that are designed to release the medication with NO RATE CONTROLLING FEATURES.	Immediate release
- These are BASED ON TIME COURSE or LOCATION OF TABLETS. - Ex: Enteric coated (To be released in the enteric region or intestine. Or other drug that are release base on time such as delayed release, extended release, repeat action, targeted release).	Modified release
Modified Release EXAMPLES	1 Extended release 2 Delayed release 3 Repeat Action 4 Targeted release EDRT
Modified Release 1 They RELEASE medication OVER AN EXTENDED PERIOD. 2 release medication at a TIME OTHER THAN PROMPTLY AFTER ADMINISTRATION. Release at certain time (After 2,4,6 hours).	. 1 Extended release 2 Delayed release
Modified Release 1) these are 2 SINGLE DOSE. 2 tablets in 1. ONE IS FOR IMMEDIATE and the OTHER IS FOR DELAYED. 2) DIRECTED TOWARDS a REGION, TISSUE OR A SITE OF ABSORPTION	. 1) Repeat Action 2 Targeted release
 These are MADE FROM WASTE MATERIAL USING TRITURATE MOLD that gives them the shape of a cut section of a cylinder.  It is USED FOR POTENT DRUGS in which tablets must be completely and rapidly soluble. (STATE THE DISADVANTAGES)	MOLDED TABLETS / TABLET TRITURATES  DISADVANTAGE: 1 In the compression of tablet, HARD TO FIND LUBRICANT esp for completely water soluble.
- It PROVIDES CONVENIENT QUANTITY OF POTENT DRUG that can be INCORPORATED READILY INTO A POWDERS &LIQUID. - Usually, they are SUPPLIED PRIMARILY AS A CONVENIENCE FOR EXTEMPORANEOUS COMPOUNDING, but it should never be dispensed as a dosage form. - In other words, they are ORDERED FOR SPECIAL PRESCRIPTIONS. Not available as commercial dosage form	Dispensing tablet also known as Compounding Tablets
- These are SOFT READILY SOLUBLE TABLETS and originally USED FOR THE PREPARATION OF SOLUTION TO BE INJECTED. - However, they are NOT AVAILABLE IN THE MARKET because of the DIFFICULTY IN ACHIEVING STERILITY. As we all know, parenteral are now available for most drug substances.	Hypodermic Tablets
- Also known as VAGINAL INSERTS. - They are BULLET or OVOID SHAPE that is inserted in vagina for local and systemic effects.	Vaginal Tablets
- Contains one or more medicinal agents in a FLAVOURED, SWEETENED BASE that is intended to be DISSOLVE SLOWLY IN THE MOUTH. (GIVE TYPES)	LOZENGES Ex. 1 Lollipops, 2 Troches, 3 Pastilles
SUGAR BASE LOZENGES ON A STICK. (GIVE EXAMPLES OF THIS)	Lollipops Ex: fentanyl citrate lollipop.
compressed lozenges in a DISCOID SHAPE. (GIVE EXAMPLES OF THIS)	Troches Ex: Difflam, Strepsils
These are MOLDED LOZENGES. They are SOFTER and has a HIGHER CONCENTRATION of SUGAR or GELATIN. (GIVE EXAMPLES OF THIS)	Pastilles Ex: Scotts pastilles
- Same as vaginal insert. - They are ALSO IN TABLET FORM that are intended for INSERTION TO DIFFERENT BODY ORIFICE.	INSERTS
- They are SMALL, STERILE SOLID DOSAGE FORM CONTAINING a CONCENTRATED DRUG for IMPLANTATION. - It CONTINUOUSLY RELEASES THE MEDICATION over long period. - Usually, they are INJECTED SUBCUTANEOUSLY.	IMPLANTS / PELLETS