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Index
»
ONCOLD1
»
Chapter 1
»
TREATMENT MODALITIES
level: TREATMENT MODALITIES
Questions and Answers List
level questions: TREATMENT MODALITIES
Question
Answer
helps the immune system to function better
BIOLOGIC THERAPY
Biologic therapy works by:
inducing the immune system to attack cancer cells; make cancer cell easier for the body to recognize
bone marrow transplants are the main treatment of choice for
leukemia and aplastic anemia
Procedure to replace the damaged/ destroyed bone marrow with healthy compatible bone marrow stem cells
Bone Marrow Transplants
soft fatty tissue inside the bones wherein it contains/ produces healthy blood cells
Bone marrow
Treats metastatic cancer
Chemotherapy
The RNA or DNA of a cell tells it how to replicate itself, and ________works by destroying this RNA or DNA.
Chemotherapy
Refers to the drugs that prevent cancer cells from dividing and growing and it does this by killing the dividing cells
Chemotherapy
Chemotherapy drugs:They work by attacking the negatively charged sites on the DNA (oxygen, nitrogen, phosphorous and sulfur atoms).
Alkylating agent.
Chemotherapy drugs:an antimetabolite that inhibits a crucial enzyme required for DNA synthesis and therefore exerts its effect on the S phase of the cell cycle.
Methotrexate
Chemotherapy drugs:They work by the formation of free oxygen radicals. These radicals result in DNA strand breakdown and subsequent inhibition of DNA synthesis and function.
Anthracyclines.
Chemotherapy drugs:also inhibit the enzyme topoisomerase by forming a complex with the enzyme and DNA.
Anthracyclines.
Chemotherapy drugs:They form free oxygen radicals that result in DNA breakdown leading to cancer cell death.
Antitumor Antibiotics.
Chemotherapy drugs:Treatment of choice for testicular cancer and Hodgkin's lymphoma
Antitumor Antibiotics.
Antitumor Antibiotics example; is an active agent in regimens for testicular cancer and Hodgkin's lymphoma
Bleomycin
Chemotherapy drugs:camptothecan analogs (also called Topoisomerase I inhibitors) act by forming a complex with Topoisomerase and DNA resulting in the inhibition and function of the Topoisomerase enzyme.
Plant alkaloid
Chemotherapy drugs:Etoposide and Teniposide are epipodophyllotoxin chemotherapy agents (also called topoisomerase II inhibitors)
Plant alkaloid
Chemotherapy drugs:bind to the tubulin and lead to the disruption of the mitotic spindle apparatus.
Vinca alkaloids
Chemotherapy drugs(Vinca alkaloids):treatment of choice for a number of types of cancer including leukemia, Hodgkin's disease and lung cancers
Vincristine
Chemotherapy drugs(Vinca alkaloids):treatment of choice for the brain cancer, bladder, melanoma and testicular cancer
Vinblastine
Chemotherapy drugs(Vinca alkaloids):breast and lung cancer
Vinorelbine
Chemotherapy drugs:Targeting the tubulin apparatus that lead to the disruption of the mitotic spindles
Vinca alkaloids
Chemotherapy drugs:The taxanes include
paclitaxel and docetaxel.
Chemotherapy drugs:They bind with high affinity to the microtubules and inhibit their normal function;
The taxanes
Chemotherapy drugs:Natural metal derivatives.
Platinums.
Chemotherapy drugs:These agents work by cross-linking DNA subunits. The resultant cross-link acts to inhibit DNA synthesis, transcription and function
Platinums.
Chemotherapy drugs:Helpful for those with prostate cancer
Platinums.
MCRPC
Metastatic Castration-Resistant Prostate Cancer
Complementary Medicine:those that are ingested or injected Herbals, vitamins, organics, chemicals and diet
CAM I
Complementary Medicine:those that require a practitioner or therapist. meditation, massage, chiropractic, acupuncture, body-mind therapy, and prayer
CAM II
Mutated or Damaged gene. This can lead to a gene not functioning properly and a cell growing uncontrollably. This can eventually lead to cancer formation.
Gene Therapy
A mutated cell undergoes process of _____- (which is reversible), gene therapy alters damaged gene
dysplasia
Examples of hormones include: estrogen, testosterone, insulin, thyroid hormone, cortisol, and epinephrine.
Hormone Therapy
block the action of these hormones could stop the cancer from growing.
Hormone Therapy
Primarily used to treat breast and prostate cancer
Hormone Therapy
novel cancer treatment which works by exposing a photosensitizing drug to specific wavelengths of light to kill cancer cells.
Photodynamic therapy (PDT)
Patient is given an injection of the light- sensitive drug.
Photodynamic therapy (PDT)
Light from a laser will be aimed at the cancer cells by the doctor. This takes approximately 5 to 40 minutes depending on the amount of cancer and extent of cance
Photodynamic therapy (PDT)
uses high energy x- rays to damage the DNA of cells, thereby killing the cancer cells, or at least stopping them from reproducing.
Radiation Oncology
also damages normal cells, but because normal cells are growing more slowly, they are better able to repair this radiation damage than are cancer cells.
Radiation Oncology
Various surgical procedures used to treat many types of cancer
Surgical Oncology