level: MODE OF ACTION
Questions and Answers List
level questions: MODE OF ACTION
| Question | Answer |
|---|---|
| Mechanism of Action NSAIDs | Act by INHIBITING THE COX enzymes that catalyze the first step in prostanoid biosynthesis (results to DECREASED PROSTAGLANDINS) |
| Mechanism of Action TRIPTANS | •SEROTONIN AGONISTS (acting at a subgroup of serotonin receptors found on small peripheral nerves that innervate the intracranial vasculature) (5-HT1B/1D) |
| ERGOT ALKALOIDS | •Binds to 5-HT1D (located on intracranial blood vessels that cause vasoconstriction), alpha receptors, and dopamine receptors |