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level: Level 5

Questions and Answers List

level questions: Level 5

Question	Answer
Autoimmune Inflammatory Demyelinating Disease of the CNS. May consist of one or two acute neurologic episodes Can be Chronic, relapsing or progressive disease that may span 10 to 20 years.	Multiple Sclerosis
Help DIMINISH the inflammatory responses that lead to demyelination of the axon sheaths. A/E: Depression, Local injection site reaction, Hepatic enzyme increases, Flu-like symptoms for MS	Interferon B1a Interferon B1b
Synthetic polypeptide that RESEMBLES MYELIN PROTEIN Act as DECOY to T-cell attack. for MS	Glatiramer
Oral DRUG ALTER LYMPHOCYTE MIGRATION, resulting in lower lymphocytes in the CNS Cause FIRST-DOSE BRADYCARDIA and associated with Increased RISK of INFECTION & MACULAR EDEMA for MS	Fingolimod
Oral pyrimidine Synthesis Inhibitor Leads to LOWER CONCENTRATION of ACTIVE LYMPHOCYTES in the CNS. May cause ELEVATED LIVER ENZYMES SHOULD BE AVOIDED IN PREGNANCY for MS	Teriflunomide
Oral Agent ALTER CELLULAR RESPONSE to OXIDATIVE STRESS to reduce disease progression A/E: FLUSHING, ABDOMINAL PAIN for MS	Dimethyl Fumarate
MONOCLONAL ANTIBODY for patients who have FAILED FIRST-LINE THERAPIES for MS	Natalizumab
Cytotoxic ANTHRACYCLINE ANALOG Kills T-cells for MS	Mitoxantrone
ORAL POTASSIUM CHANNEL BLOCKER IMPROVES WALKING SPEEDS in patients with MS symptomatic treatment	Dalfampridine
The ONLY drug indicated for ALS (Amyotrophic Lateral Sclerosis) NMDA receptor antagonist Inhibits glutamate release and blocks sodium channels IMPROVE SURVIVAL TIME and delay the need for bentilator support	Riluzole