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level: Level 4

Questions and Answers List

Question	Answer
ANTIMUSCARINIC AGENTS Much LESS efficacious than Levodopa ADJUVANT role in Antiparkinsonism Therapy INDUCE mood changes, xerostomia, constipation, visual problems, interfere with gastrointestinal peristalsis CONTRAINDICATED in: GLAUCOMA, Prostatic Hyperplasia, Pyloric Stenosis	1 Benztropine 2 Trihexyphenidyl 3 Procyclidine 4 Biperiden
Dementia three distinguishing features	1 Accumulation of SENILE PLAQUES 2 Forms numerous NEUROFIBRILLARY TANGLES 3 Loss of CORTICAL NEURONS SINO C
1 are deposits of a protein fragment called beta-amyloid that build up in the spaces between nerve cells 2 are twisted fibers of another protein called tau that build up inside cells	1 Plaques 2 Tangles
REVERSIBLE AChE Inhibitors for MILD TO MODERATE Alzheimer's	1 Donepezil 2 Galantamine 3 Rivastigmine
Only agent approved for the Management of DEMENTIA ASSOCIATED with PARKINSON'S DISEASE Available as TRANSDERMAL FORMULATION	Rivastigmine
AChE Inhibitor may augment action of ACh at nicotinic receptors in CNS	Galantamine
NMDA Receptor Antagonist for MODERATE TO SEVERE ALZHEIMER'S DISEASE Limits Ca2+ Influx S/E: Confusion, Agitation, Restlessness	Memantine