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Index
»
PHARMACOLOGY 1
»
ANTIPSYCHOTICS CHAPTER 11
»
Level 4
level: Level 4
Questions and Answers List
ATYPICAL DRUGS: Ring Analogs of Phenothiazines
level questions: Level 4
Question
Answer
1 • Daxolin® 2 • Seroquel® 3 • Risperdal®
1 Loxapine 2 Quetiapine 3 Risperidone
• has proved EFFECTIVE even in CHRONICALLY ILL PATIENTS who respond POORLY TO STANDARD NEUROLEPTICS • used to reduce SUICIDAL RISK ONLY drug that does not cause EPS • S/E: SEVERE AGRANULOCYTOSIS, seizure, myocarditis
Clozapine • Clozaril®
Management of DISRUPTIVE BEHAVIOUR and IRRITABILITY secondary to AUTISM
Risperidone
• a more potent antagonist at D2 and 5- HT2A receptors • can INDUCE WEIGHT GAIN, TYPE 2 DIABETES & HYPERLIPIDEMIA
Olanzapine • Zyprexa®
• can cause/PROMOTE ARRYTHMIA
Ziprasidone •Geodon®
Management of DISRUPTIVE BEHAVIOUR and IRRITABILITY secondary autism • DOPAMINE AGONIST-ANTAGONIST • NEWEST antipsychotic agent • LESSER WEIGHT GAIN
Aripiprazole • Abilify®
Treatment for BIPOLAR DISORDER Available as SUBLINGUAL
Asenapine
Used in SCHIZOAFFECTIVE DISORDER
Paliperidone
Treatment for BIPOLAR disorder ADJUNCTIVE treatment for MAJOR DEPRESSION also causes SEDATION (strong antihistaminergic effect)
Quetiapine
The administration of this minimizes EXTRAPYRAMIDAL EFFECTS (more effective for pseudoparkinsonism and acute dystonia) Anticholinergic
Benztropine
DRUG OF CHOICE for management of ANTIPSYCHOTIC-INDUCED AKATHISIA
Propranolol