level: MODE OF ACTION
Questions and Answers List
level questions: MODE OF ACTION
| Question | Answer |
|---|---|
| BENZODIAZEPINES MOA | • induce conformational (allosteric) changes in the GABA-binding site, thereby increasing the affinity of the receptors for GABA • Result: the FREQUENCY of Cl-channel openings is increased |
| BARBITURATES MOA | • potentiate GABA action on chloride entry into the neuron by increasing the duration of opening of chloride channels |